STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2FKI4Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (437 aa)    
Predicted Functional Partners:
A0A1Y2F476
Autophagy-related protein.
   
 0.995
A0A1Y2FWQ4
Kinase-like domain-containing protein.
   
 
 0.970
A0A1Y2FKD2
Triacylglycerol lipase.
   
 
 0.960
A0A1Y2F239
Autophagy-related protein 3.
   
 
 0.797
A0A1Y2FL22
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 
 0.725
A0A1Y2FQZ9
WD40-repeat-containing domain protein.
   
 
 0.722
A0A1Y2F8W6
Autophagy protein Apg6-domain-containing protein.
    
 
 0.651
A0A1Y2FWV3
Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.
   
 
 0.634
A0A1Y2F861
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
  
 0.619
A0A1Y2FTH6
Uncharacterized protein.
    
 
 0.563
Your Current Organism:
Protomyces lactucaedebilis
NCBI taxonomy Id: 56484
Other names: NRRL YB-4353, P. lactucaedebilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.