STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2FSA11-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (269 aa)    
Predicted Functional Partners:
A0A1Y2F414
Histidine biosynthesis trifunctional protein.
  
 
 0.996
A0A1Y2FK56
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
  
 
 0.993
A0A1Y2F8Z0
ATP phosphoribosyltransferase.
  
 
 0.990
A0A1Y2FP26
Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
  
 
 0.990
A0A1Y2FK07
Glutamine amidotransferase class-I-domain-containing protein.
  
 
 0.971
A0A1Y2FM30
Putative anthranilate synthase multifunctional protein TrpC.
  
 
 0.971
A0A1Y2FAD0
SNF2 family N-terminal domain-domain-containing protein.
  
 
 0.968
A0A1Y2F7T1
Pyridoxal phosphate-dependent transferase.
  
  
 0.964
A0A1Y2F1E6
Tryptophan synthase.
  
 
 0.919
A0A1Y2FMH9
Glycosyl transferase family, a/b domain-domain-containing protein.
    
 0.873
Your Current Organism:
Protomyces lactucaedebilis
NCBI taxonomy Id: 56484
Other names: NRRL YB-4353, P. lactucaedebilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.