STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2FSZ2WD_REPEATS_REGION domain-containing protein. (316 aa)    
Predicted Functional Partners:
A0A1Y2EZF4
WD40-repeat-containing domain protein.
   
 0.978
A0A1Y2F8Q4
B30.2/SPRY domain-containing protein.
    
 0.975
A0A1Y2FEW5
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
   
 0.972
A0A1Y2FDP5
PHD domain-containing protein.
    
 
 0.943
A0A1Y2FYA4
WD repeat-containing protein pop3.
 
  
 
0.912
A0A1Y2FSY8
WD_REPEATS_REGION domain-containing protein.
 
    
0.856
A0A1Y2FDJ6
TPR_REGION domain-containing protein.
    
 0.853
A0A1Y2FCD6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.842
A0A1Y2FFQ0
Histone H2A; Belongs to the histone H2A family.
   
  0.838
A0A1Y2FR23
Histone acetyltransferase GCN5.
    
 0.810
Your Current Organism:
Protomyces lactucaedebilis
NCBI taxonomy Id: 56484
Other names: NRRL YB-4353, P. lactucaedebilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.