STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GACE_0108Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. (249 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.996
GACE_1260
Siroheme synthase.
 
 
 0.981
GACE_1792
Cobalt-precorrin-3b C17-methyltransferase.
  
  
 0.954
GACE_1786
Uroporphyrinogen-III synthase.
 
 
 0.942
GACE_0111
Porphobilinogen synthase; Belongs to the ALAD family.
  
  
 0.929
GACE_1093
Ferredoxin--nitrite reductase.
 
  
 0.928
GACE_1795
Cobalt-precorrin-2 C20-methyltransferase.
  
 
 0.927
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.907
GACE_1800
Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 
0.906
hemL
Glutamate-1-semialdehyde aminotransferase.
     
 0.836
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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