Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GACE_0262Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (295 aa)    
Predicted Functional Partners:
GACE_0124
Citrate synthase.
  
 0.999
GACE_0933
Isocitrate dehydrogenase (NADP-dependent).
  
 0.988
GACE_1870
Fumarate hydratase, subunit alpha.
  
 
 0.983
GACE_0422
NADP-dependent malic enzyme.
  
 0.980
GACE_1871
Fumarate hydratase, subunit beta.
  
 
 0.975
GACE_1545
Oxaloacetate decarboxylase subunit alpha.
    
 0.962
GACE_0283
Phosphoenolpyruvate carboxylase.
     
 0.954
GACE_1453
Aspartate aminotransferase.
  
 0.936
rpl4
LSU ribosomal protein L1e (L4p); Forms part of the polypeptide exit tunnel.
  
 0.936
gap
Glyceraldehyde-3-phosphate dehydrogenase NAD(P)-dependent, phosphorylating.
  
 
 0.918
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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