Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
GACE_0932CoB--CoM heterodisulfide reductase subunit C. (155 aa)    
Predicted Functional Partners:
GACE_0706
CoB--CoM heterodisulfide reductase subunit A.
 
 0.999
GACE_0931
CoB--CoM heterodisulfide reductase subunit B.
 
 0.999
GACE_0709
Methylviologen-reducing hydrogenase, subunit delta (MvhD).
 
 0.998
GACE_1881
Heterodisulfide reductase, subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.998
GACE_0708
CoB--CoM heterodisulfide reductase subunit B.
 
 0.997
GACE_0710
Methylviologen-reducing hydrogenase, subunit gamma (MvhG).
 
 0.995
GACE_0711
Methylviologen-reducing hydrogenase, subunit alpha (MvhA).
 
 0.995
GACE_0707
CoB--CoM heterodisulfide reductase subunit C.
  
  
  0.966
GACE_1903
Heterodisulfide reductase iron-sulfur subunit D.
 
 
 0.945
GACE_1353
N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H.
 
  
 0.918
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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