Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
GACE_1812Biotin-protein ligase. (307 aa)    
Predicted Functional Partners:
GACE_0561
Biotin carboxylase of acetyl-CoA carboxylase.
 0.984
GACE_0750
methylmalonyl-CoA decarboxylase, subunit alpha.
 
 
 0.896
GACE_0319
Substrate-specific component BioY of biotin ECF transporter.
 
   
 0.877
GACE_1545
Oxaloacetate decarboxylase subunit alpha.
 
     0.751
GACE_1813
Ribosomal-protein-S18p-alanine acetyltransferase.
 
   
 0.731
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
 0.725
GACE_0790
MaoC family protein.
  
  
 0.611
GACE_1245
Aldehyde dehydrogenase.
  
  
 0.611
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.606
GACE_0777
2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase, BadH.
 
  
 0.604
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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