Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ilvEHypothetical protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (292 aa)    
Predicted Functional Partners:
GACE_0436
2-isopropylmalate synthase.
 
 0.995
GACE_1898
Homoserine dehydrogenase.
 
 
 0.995
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.994
GACE_1897
Peptidase A24B, FlaK-like.
     
 0.944
GACE_1899
ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase.
       0.944
GACE_2028
Threonine dehydratase.
  
 0.943
GACE_2156
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.935
GACE_2154
2-ketoisovalerate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.918
cimA
2-isopropylmalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.887
GACE_0696
Pyruvate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.837
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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