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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GACE_2000Hypothetical protein. (222 aa)    
Predicted Functional Partners:
GACE_1999
Replication protein A.
 
   
 0.951
GACE_2001
Aspartate aminotransferase.
       0.775
GACE_1959
Hypothetical protein.
 
     0.718
GACE_0678
Hypothetical protein.
  
     0.705
GACE_0952
Cytochrome oxidase, subunit I.
  
     0.697
GACE_0367
Signal peptidase I.
  
     0.692
GACE_1339
Hypothetical protein.
 
     0.658
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.652
GACE_2024
Archaeosine tRNA-ribosyltransferase type 2.
  
     0.650
GACE_0114
Transcriptional regulator, ArsR family.
  
     0.637
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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