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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GACE_2002Hypothetical protein. (171 aa)    
Predicted Functional Partners:
GACE_0133
Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative.
 
 
 
 0.871
GACE_0768
acetyl-CoA synthetase.
 
 
 
 0.855
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
     
 0.694
GACE_1600
DNA double-strand break repair protein Mre11.
 
    0.652
cobB
Transcriptional regulatory protein, Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.622
cobB-2
NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.622
GACE_0422
NADP-dependent malic enzyme.
   
 
 0.613
GACE_0262
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
     
 0.603
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.600
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
     
 0.574
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
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