Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GACE_2169ATP--cobalamin adenosyltransferase. (164 aa)    
Predicted Functional Partners:
GACE_1792
Cobalt-precorrin-3b C17-methyltransferase.
     
 0.979
GACE_1805
Cobyrinic acid A,C-diamide synthase.
 
  
 0.939
GACE_1857
Adenosylcobinamide amidohydrolase.
  
 
  0.939
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
    
 0.933
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
    
 0.931
GACE_2171
Methylmalonyl-CoA mutase, C-terminal domain/subunit.
     
 0.817
GACE_2170
LAO/AO transport system ATPase.
       0.811
GACE_2168
Transcriptional regulatory protein, putative.
       0.792
GACE_2172
Methylmalonyl-CoA mutase, N-terminal domain/subunit.
       0.738
GACE_2173
Pimeloyl-CoA dehydrogenase, small subunit PimD.
  
    0.607
Your Current Organism:
Geoglobus acetivorans
NCBI taxonomy Id: 565033
Other names: DSM 21716, G. acetivorans, Geoglobus acetivorans Slobodkina et al. 2009, Geoglobus sp. SBH6, VKM B-2522, strain SBH6
Server load: low (14%) [HD]