STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED34468.1[E] COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family. (512 aa)    
Predicted Functional Partners:
EED35682.1
[E] COG0070 Glutamate synthase domain 3.
 
0.998
EED34515.1
Glutamate synthase small chain; [O] COG0492 Thioredoxin reductase.
 
 0.997
EED35195.1
4Fe-4S ferredoxin, iron-sulfur binding; [O] COG0492 Thioredoxin reductase.
 
 0.991
gdhA
[E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.938
EED34929.1
[E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.938
guaA_1
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.856
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 0.831
EED36371.1
Proline dehydrogenase family protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 
 0.716
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.663
EED36507.1
Signal transduction protein; [T] COG2200 FOG: EAL domain.
       0.631
Your Current Organism:
Luminiphilus syltensis
NCBI taxonomy Id: 565045
Other names: L. syltensis NOR5-1B, Luminiphilus syltensis NOR5-1B, gamma proteobacterium Ivo14
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