STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LBRM_21_1390ATP-dependent DNA helicase; Belongs to the helicase family. (788 aa)    
Predicted Functional Partners:
LBRM_15_1440
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.496
LBRM_06_0830
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.491
LBRM_16_0010
Anti-silencing protein a-like protein.
   
 
 0.469
LBRM_20_4140
Contig, possible fusion of chromosomes 20 and 34.
   
 
 0.469
LBRM_32_1890
DNA_pol_E_B domain-containing protein.
   
 
 0.466
LBRM_09_0670
Putative ATP-dependent DNA helicase.
  
 
 0.460
LBRM_28_0550
RAD50 DNA repair-like protein.
  
 
 0.443
LBRM_15_1470
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
 
  0.425
LBRM_24_1330
Putative ATP-dependent DEAD/H DNA helicase recQ.
  
 
 0.418
LBRM_30_2240
ATP-dependent DEAD/H DNA helicase recQ family-like protein.
  
 
 0.418
Your Current Organism:
Leishmania braziliensis
NCBI taxonomy Id: 5660
Other names: L. braziliensis, Leishmania (V.) braziliensis, Leishmania (Viannia) braziliensis, Leishmania brasiliensis, Leishmania viannia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.