STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_27_2320Protein phosphatase-like protein. (314 aa)    
Predicted Functional Partners:
LMJF_33_1240
WD_REPEATS_REGION domain-containing protein.
   
 0.552
LMJF_32_2240
Putative methionyl-tRNA formyltransferase.
  
   0.549
LMJF_27_1440
Uncharacterized protein.
 
      0.439
LMJF_11_0690
ANK_REP_REGION domain-containing protein.
  
 0.419
DHFR-TS
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.
  
    0.413
LMJF_07_0370
Uncharacterized protein.
   
 0.408
LMJF_29_2490
Protein kinase domain-containing protein.
  
 0.402
LMJF_36_4380
Alternative oxidase.
  
 0.402
LMJF_32_3050
Roc domain-containing protein.
  
 0.402
LMJF_31_1840
Protein kinase domain-containing protein.
  
 0.402
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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