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LmjF.14.1190 protein (Leishmania major) - STRING interaction network
"LmjF.14.1190" - Bifunctional NAD(P)H-hydrate repair enzyme in Leishmania major
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some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LmjF.14.1190Bifunctional NAD(P)H-hydrate repair enzyme; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity); In the N-terminal section; belongs to the NnrE/AIBP family (560 aa)    
Predicted Functional Partners:
LmjF.35.0370
ATP-dependent DEAD-box RNA helicase, putative.[Source-GeneDB;Acc-LmjF.35.0370]; Belongs to the DEAD box helicase family (405 aa)
   
 
  0.992
LmjF.32.0630
Hypothetical protein, conserved.[Source-GeneDB;Acc-LmjF.32.0630] (186 aa)
   
   
  0.939
SPL
Sphingosine phosphate lyase-like protein, putative.[Source-GeneDB;Acc-LmjF.30.2350] (537 aa)
   
   
  0.931
LmjF.16.0420
Hypothetical protein, conserved.[Source-GeneDB;Acc-LmjF.16.0420] (571 aa)
   
        0.930
LmjF.09.0950
O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis (595 aa)
   
        0.930
LmjF.24.2130
Ubiquitin-conjugating enzyme e2, putative.[Source-GeneDB;Acc-LmjF.24.2130]; Belongs to the ubiquitin-conjugating enzyme family (155 aa)
     
      0.918
LmjF.36.6120
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (322 aa)
         
  0.917
MAR1
Ribonuclease mar1.[Source-GeneDB;Acc-LmjF.12.0060] (192 aa)
   
        0.917
LmjF.08.0320
Mitochondrial associated ribonuclease, putative.[Source-GeneDB;Acc-LmjF.08.0320] (225 aa)
   
        0.917
LmjF.08.0310
Hypothetical protein, unknown function.[Source-GeneDB;Acc-LmjF.08.0310] (311 aa)
   
        0.917
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania major, Leishmania tropica major
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