STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_36_0470Dihydrouridine synthase domain protein-like protein. (455 aa)    
Predicted Functional Partners:
LMJF_18_1220
Putative prolyl-tRNA synthetase.
  
 
 0.970
LMJF_30_3240
Putative glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.650
LMJF_18_1210
Putative prolyl-tRNA synthetase.
  
 
 0.648
LMJF_13_0940
Putative N(2), N(2)-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
   
 
 0.630
LMJF_20_1670
Putative ribosome biogenesis protein.
   
    0.625
LMJF_16_0310
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
   
  
 0.585
LMJF_28_2400
tRNA (adenine(58)-N(1))-methyltransferase.
   
  
 0.578
LMJF_32_1970
Probable ribosome biogenesis protein LMJF_32_1970; Probable pre-rRNA processing protein involved in ribosome biogenesis.
   
  
 0.557
LMJF_30_1550
tRNA pseudouridine synthase.
  
 
 0.554
LMJF_28_1740
SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.539
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.