STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_34_2590Putative adaptor complex subunit medium chain 3; Belongs to the adaptor complexes medium subunit family. (468 aa)    
Predicted Functional Partners:
LMJF_36_5260
Putative adaptin.
   
 0.999
LMJF_08_0090
AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family.
   
 0.999
LMJF_24_1540
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
 
 0.961
LMJF_34_3970
AP-1 complex subunit gamma.
   
 0.894
LMJF_07_0050
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.870
LMJF_36_3030
Clathrin coat assembly protein-like protein; Belongs to the adaptor complexes medium subunit family.
     
0.622
LMJF_36_1630
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 
 0.533
LMJF_34_2330
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
 0.524
LMJF_24_2130
Putative ubiquitin-conjugating enzyme e2; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.459
LMJF_33_1030
Uncharacterized protein.
      
 0.424
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.