STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_34_2480Uncharacterized protein. (1069 aa)    
Predicted Functional Partners:
LMJF_08_0140
Putative DNA repair protein.
    
 0.809
LMJF_35_4280
SAS-6_N domain-containing protein.
   
 0.695
LMJF_15_0270
Putative replication Factor A 28 kDa subunit.
   
 0.695
LMJF_34_4150
Uncharacterized protein.
    
 0.657
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.657
LMJF_03_0110
Uncharacterized protein.
    
 0.649
LMJF_36_3790
Calponin-homology (CH) domain-containing protein.
    
 0.649
LMJF_31_2670
Uncharacterized protein.
    
 0.649
LMJF_19_1390
Transcription initiation factor-like protein (TFIID-like protein).
    
   0.631
LMJF_25_1290
NPL4 domain-containing protein.
    
 0.600
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.