STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_34_1270Piezo_RRas_bdg domain-containing protein. (1850 aa)    
Predicted Functional Partners:
LMJF_09_0250
DNA helicase.
   
 0.852
LMJF_12_1220
Mcl1_mid domain-containing protein.
   
 
 0.729
LMJF_33_2320
Putative cell division cycle 45 (CDC45).
    
 0.712
LMJF_19_1470
Protein kinase domain-containing protein.
    
 
 0.688
LMJF_17_0060
Putative mitogen-activated protein kinase kinase 3.
    
 
 0.688
LMJF_32_1460
Putative phosphatidylinositol 3-related kinase; Belongs to the PI3/PI4-kinase family.
   
 
 0.667
LMJF_35_4910
Putative DNA replication factor; Belongs to the MCM family.
   
 0.590
LMJF_28_0850
DNA helicase.
   
 0.590
ARPC1
Putative ARP2/3 complex subunit.
   
    0.540
LMJF_35_4360
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 
 0.525
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.