STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_33_1930Putative phosphoribosyl transferase. (356 aa)    
Predicted Functional Partners:
LMJF_24_2060
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.945
LMJF_34_3780
Phosphomannomutase-like protein; Belongs to the phosphohexose mutase family.
  
 0.931
LMJF_27_0420
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. Specifically phosphorylates D-ribose. Fails to phosphorylate 4, 5 or 6 D-carbon sugars (erythrose, threose, xylulose, arabinose, fructose and glucose); Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
   
 0.928
LMJF_28_1970
Putative ribose 5-phosphate isomerase.
    
 0.926
LMJF_16_0550
Putative OMPDCase-OPRTase.
  
 
 0.923
LMJF_21_0640
Putative phosphoglucomutase; Belongs to the phosphohexose mutase family.
   
 
 0.909
LMJF_36_5390
Putative phosphoribosylpyrophosphate synthetase.
  
  
 
0.806
LMJF_08_1130
Phosphoribosylpyrophosphate synthetase.
  
  
 
0.806
LMJF_08_0510
Putative ribose-phosphate pyrophosphokinase.
     
 
0.800
LMJF_35_0050
Putative 2-oxoisovalerate dehydrogenase beta subunit, mitochondrial.
  
 0.759
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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