STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADOMETCS-adenosylmethionine decarboxylase proenzyme. (382 aa)    
Predicted Functional Partners:
LMJF_04_0580
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
    
 0.993
LMJF_30_3120
Putative S-adenosylmethionine decarboxylase proenzyme-like.
    
0.980
METK2
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
   
 
 0.940
LMJF_12_0280
Putative ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
 
  
 
 0.904
LMJF_25_1200
Modification methylase-like protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.901
LMJF_35_1480
Arginase; Belongs to the arginase family.
   
  
 0.848
EIF5A2
Eukaryotic translation initiation factor 5A.
      
 0.693
DHS34
Deoxyhypusine synthase.
    
 
 0.618
LMJF_20_0250
Putative deoxyhypusine synthase.
    
 
 0.618
LMJF_26_1910
Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.
   
  
 0.597
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.