STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSP70.4Heat shock protein 70-related protein; Belongs to the heat shock protein 70 family. (641 aa)    
Predicted Functional Partners:
LMJF_34_0030
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.985
LMJF_08_0530
Protein kinase domain-containing protein.
    
 0.985
LMJF_35_4710
Uncharacterized protein.
  
0.870
LMJF_20_1130
DNAj-like protein.
   
 0.858
UB-EP52
Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...]
   
 0.838
LMJF_24_0140
Ankyrin/TPR repeat protein.
  
 0.827
LMJF_28_1200
Putative glucose-regulated protein 78; Belongs to the heat shock protein 70 family.
  
0.789
LMJF_06_0250
Uncharacterized protein.
    
 0.784
LMJF_33_2390
Putative heat shock protein.
  
 0.777
HSP83-8
Heat shock protein 83-1.
 
 0.777
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.