STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_26_0240Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (182 aa)    
Predicted Functional Partners:
LmjF.01.0770
Probable eukaryotic initiation factor 4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
     
 0.620
LMJF_15_0060
Putative eukaryotic initiation factor 4a.
     
 0.618
LMJF_36_6060
Putative eukaryotic initiation factor 4a.
     
 0.543
EIF4G3
Putative eukaryotic translation initiation factor 4 gamma.
     
 0.543
LMJF_15_1320
Putative eukaryotic initiation factor 4a.
     
 0.543
LMJF_10_1080
Putative eukaryotic translation initation factor 4 gamma.
     
 0.543
LMJF_02_0460
Uncharacterized protein.
     
  0.540
EIF4E1
Putative eukaryotic translation initiation factor eIF-4E; Belongs to the eukaryotic initiation factor 4E family.
     
  0.540
LMJF_36_3210
14-3-3 protein-like protein; Belongs to the 14-3-3 family.
     
  0.540
LMJF_36_0590
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
     
 
0.540
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.