LMJF_22_0640 protein (Leishmania major) - STRING interaction network

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Score

LMJF_22_0640

Uncharacterized protein. (1787 aa)

Predicted Functional Partners:

LMJF_02_0630

0.617

LMJF_32_3140

0.617

LMJF_30_0610

0.614

DHFR-TS

0.575

LMJF_16_1130

0.561

LMJF_13_1100

0.561

LMJF_06_0950

0.558

LMJF_21_0420

0.553

LMJF_28_2205

0.519

LMJF_32_1670

0.506

Your Current Organism:

Leishmania major

NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHFR-TS	LMJF_02_0630	P07382	E9ACD7	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Gamma-glutamyl phosphate reductase-like protein.	0.674
DHFR-TS	LMJF_06_0950	P07382	Q4QIY2	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Putative glucosamine-fructose-6-phosphate aminotransferase.	0.476
DHFR-TS	LMJF_13_1100	P07382	Q4QG44	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Putative leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.407
DHFR-TS	LMJF_16_1130	P07382	Q4QEQ4	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Tyrosyl or methionyl-tRNA synthetase-like protein.	0.741
DHFR-TS	LMJF_22_0640	P07382	Q4QBT3	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.575
DHFR-TS	LMJF_30_0610	P07382	Q4Q7P5	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Putative nitrate reductase.	0.556
DHFR-TS	LMJF_32_3140	P07382	Q4Q4V8	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Pyrroline-5-carboxylate synthetase-like protein.	0.674
LMJF_02_0630	DHFR-TS	E9ACD7	P07382	Gamma-glutamyl phosphate reductase-like protein.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.674
LMJF_02_0630	LMJF_06_0950	E9ACD7	Q4QIY2	Gamma-glutamyl phosphate reductase-like protein.	Putative glucosamine-fructose-6-phosphate aminotransferase.	0.513
LMJF_02_0630	LMJF_16_1130	E9ACD7	Q4QEQ4	Gamma-glutamyl phosphate reductase-like protein.	Tyrosyl or methionyl-tRNA synthetase-like protein.	0.682
LMJF_02_0630	LMJF_21_0420	E9ACD7	Q4QCH3	Gamma-glutamyl phosphate reductase-like protein.	Ferredoxin NADP+ reductase-like protein.	0.631
LMJF_02_0630	LMJF_22_0640	E9ACD7	Q4QBT3	Gamma-glutamyl phosphate reductase-like protein.	Uncharacterized protein.	0.617
LMJF_02_0630	LMJF_30_0610	E9ACD7	Q4Q7P5	Gamma-glutamyl phosphate reductase-like protein.	Putative nitrate reductase.	0.487
LMJF_02_0630	LMJF_32_3140	E9ACD7	Q4Q4V8	Gamma-glutamyl phosphate reductase-like protein.	Pyrroline-5-carboxylate synthetase-like protein.	0.995
LMJF_06_0950	DHFR-TS	Q4QIY2	P07382	Putative glucosamine-fructose-6-phosphate aminotransferase.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.476
LMJF_06_0950	LMJF_02_0630	Q4QIY2	E9ACD7	Putative glucosamine-fructose-6-phosphate aminotransferase.	Gamma-glutamyl phosphate reductase-like protein.	0.513
LMJF_06_0950	LMJF_16_1130	Q4QIY2	Q4QEQ4	Putative glucosamine-fructose-6-phosphate aminotransferase.	Tyrosyl or methionyl-tRNA synthetase-like protein.	0.651
LMJF_06_0950	LMJF_21_0420	Q4QIY2	Q4QCH3	Putative glucosamine-fructose-6-phosphate aminotransferase.	Ferredoxin NADP+ reductase-like protein.	0.507
LMJF_06_0950	LMJF_22_0640	Q4QIY2	Q4QBT3	Putative glucosamine-fructose-6-phosphate aminotransferase.	Uncharacterized protein.	0.558
LMJF_06_0950	LMJF_32_1670	Q4QIY2	Q4Q5B3	Putative glucosamine-fructose-6-phosphate aminotransferase.	Putative NAD+ synthase.	0.426