LMJF_17_0910 protein (Leishmania major) - STRING interaction network

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Score

LMJF_17_0910

PlsC domain-containing protein. (477 aa)

Predicted Functional Partners:

DHFR-TS

0.694

LMJF_32_1960

0.649

LMJF_36_2580

0.531

LMJF_09_0490

0.495

LMJF_29_2730

0.409

LMJF_11_0880

0.409

Your Current Organism:

Leishmania major

NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHFR-TS	LMJF_09_0490	P07382	Q4QHX5	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.694
DHFR-TS	LMJF_17_0910	P07382	Q4QE99	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	PlsC domain-containing protein.	0.694
DHFR-TS	LMJF_32_1960	P07382	Q4Q582	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Putative 1-acyl-sn-glycerol-3-phosphateacyltransferase.	0.694
DHFR-TS	LMJF_36_2580	P07382	Q4Q1G3	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	Related to multifunctional cyclin-dependent kinase pho85-like protein.	0.557
LMJF_09_0490	DHFR-TS	Q4QHX5	P07382	Uncharacterized protein.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.694
LMJF_09_0490	LMJF_17_0910	Q4QHX5	Q4QE99	Uncharacterized protein.	PlsC domain-containing protein.	0.495
LMJF_09_0490	LMJF_32_1960	Q4QHX5	Q4Q582	Uncharacterized protein.	Putative 1-acyl-sn-glycerol-3-phosphateacyltransferase.	0.770
LMJF_09_0490	LMJF_36_2580	Q4QHX5	Q4Q1G3	Uncharacterized protein.	Related to multifunctional cyclin-dependent kinase pho85-like protein.	0.536
LMJF_11_0880	LMJF_17_0910	Q4QGZ1	Q4QE99	START domain-containing protein.	PlsC domain-containing protein.	0.409
LMJF_11_0880	LMJF_32_1960	Q4QGZ1	Q4Q582	START domain-containing protein.	Putative 1-acyl-sn-glycerol-3-phosphateacyltransferase.	0.406
LMJF_17_0910	DHFR-TS	Q4QE99	P07382	PlsC domain-containing protein.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.694
LMJF_17_0910	LMJF_09_0490	Q4QE99	Q4QHX5	PlsC domain-containing protein.	Uncharacterized protein.	0.495
LMJF_17_0910	LMJF_11_0880	Q4QE99	Q4QGZ1	PlsC domain-containing protein.	START domain-containing protein.	0.409
LMJF_17_0910	LMJF_29_2730	Q4QE99	E9AED5	PlsC domain-containing protein.	START domain-containing protein.	0.409
LMJF_17_0910	LMJF_32_1960	Q4QE99	Q4Q582	PlsC domain-containing protein.	Putative 1-acyl-sn-glycerol-3-phosphateacyltransferase.	0.649
LMJF_17_0910	LMJF_36_2580	Q4QE99	Q4Q1G3	PlsC domain-containing protein.	Related to multifunctional cyclin-dependent kinase pho85-like protein.	0.531
LMJF_29_2730	LMJF_17_0910	E9AED5	Q4QE99	START domain-containing protein.	PlsC domain-containing protein.	0.409
LMJF_29_2730	LMJF_32_1960	E9AED5	Q4Q582	START domain-containing protein.	Putative 1-acyl-sn-glycerol-3-phosphateacyltransferase.	0.406
LMJF_32_1960	DHFR-TS	Q4Q582	P07382	Putative 1-acyl-sn-glycerol-3-phosphateacyltransferase.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.	0.694
LMJF_32_1960	LMJF_09_0490	Q4Q582	Q4QHX5	Putative 1-acyl-sn-glycerol-3-phosphateacyltransferase.	Uncharacterized protein.	0.770