STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_14_0350Putative threonine synthase. (676 aa)    
Predicted Functional Partners:
LMJF_30_3080
Putative homoserine kinase.
 
 
 0.999
LMJF_07_0260
Homoserine dehydrogenase.
 
 
 0.991
LMJF_01_0480
Putative beta eliminating lyase.
  
 0.955
LMJF_06_0730
Putative serine-threonine dehydratase.
  
  
 0.793
LMJF_03_0030
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.774
LMJF_33_2550
Isocitrate dehydrogenase [NADP].
  
 
 0.711
LMJF_23_0260
Putative argininosuccinate synthase.
  
  
 0.706
LMJF_28_1580
Phosphonopyruvate decarboxylase-like protein.
  
  
 0.694
LMJF_27_2030
Putative branched-chain amino acid aminotransferase.
  
 
 0.686
LMJF_02_0630
Gamma-glutamyl phosphate reductase-like protein.
  
  
 0.673
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.