STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATG8C.12Autophagy-related protein. (134 aa)    
Predicted Functional Partners:
LMJF_07_0010
Putative ubiquitin activating E1 enzyme.
   
 0.811
LMJF_33_0295
Autophagy-related protein 3.
   
 0.654
ATG4.1
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
   
 0.640
ATG4.2
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
   
 0.640
LMJF_21_0823
Protein kinase domain-containing protein.
   
 0.543
LMJF_10_0830
Protein kinase domain-containing protein.
   
 0.543
SPL
Sphingosine-1-phosphate lyase.
   
  
 0.511
LMJF_34_3350
ATPase-like protein; Belongs to the AAA ATPase family.
      
 0.506
VPS4
Vacuolar protein sorting-associated protein 4; Belongs to the AAA ATPase family.
      
 0.500
ATG5
Autophagy protein 5 (ATG5).
      
 0.497
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.