STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMJF_07_0100Pitrilysin-like metalloprotease; Belongs to the peptidase M16 family. (1032 aa)    
Predicted Functional Partners:
LMJF_19_0550
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
  
 
 0.812
LMJF_18_1380
Putative pyruvate dehydrogenase E1 component alpha subunit.
   
   0.704
LMJF_25_1050
Frataxin-like protein.
     
 0.624
LMJF_36_4450
Putative mitochondrial intermediate peptidase.
    
 
 0.538
LMJF_25_1180
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
    
  0.537
LMJF_25_1170
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
    
  0.537
SCG5-2
Phosphoglycan beta 1,3 galactosyltransferase 5; Belongs to the peptidase M16 family.
    
 
 0.530
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
  
 
 0.526
LMJF_30_3010
Uncharacterized protein.
   
    0.516
KATNA1
Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.
    
 
 0.511
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.