STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BT1-2Biopterin transporter,putativewith. (631 aa)    
Predicted Functional Partners:
DHFR-TS
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.
  
  
 0.735
LMJF_22_0420
Putative 40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
  
 0.575
LMJF_11_1050
Putative pretranslocation protein,alpha subunit.
  
  
 0.575
LMJF_16_0140
Putative eukaryotic translation initiation factor 1A.
  
  
 0.573
RPL11
60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
  
 0.568
LMJF_15_0950
Putative 40S ribosomal protein S3.
  
  
 0.567
LMJF_11_1190
Putative 40S ribosomal protein S15A; Belongs to the universal ribosomal protein uS8 family.
  
  
 0.567
LMJF_11_0960
40S ribosomal protein S5A.
  
   0.538
LMJF_26_2330
Putative 60S ribosomal protein L35.
  
  
 0.534
LMJF_06_0570
Putative 60S ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
  
    0.523
Your Current Organism:
Leishmania major
NCBI taxonomy Id: 5664
Other names: L. major, Leishmania (Leishmania) major, Leishmania tropica major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.