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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
Score
add_1Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (339 aa)    
Predicted Functional Partners:
EED32513.1
[R] COG2236 Predicted phosphoribosyltransferases.
  
  0.795
EED32514.1
[P] COG0659 Sulfate permease and related transporters (MFS superfamily).
       0.785
NOR53_18
Hypothetical protein; [R] COG1073 Hydrolases of the alpha/beta superfamily.
    
  0.750
EED32894.1
Cytosolic 5'-nucleotidase 1A; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
     
  0.743
NOR53_390
HAD-superfamily hydrolase subfamily IA, variant 3; [R] COG0637 Predicted phosphatase/phosphohexomutase.
     
  0.743
xdhB
Xanthine dehydrogenase, molybdopterin binding subunit; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.
 
  
 0.594
EED33076.1
Purine phosphorylase, family 2; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
  
 
 0.562
xdhA
[C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.
    
  0.528
iunH_2
[F] COG1957 Inosine-uridine nucleoside N-ribohydrolase; Belongs to the IUNH family.
 
 
 0.525
soxB
Sulfur oxidation protein SoxB; [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.
    
  0.512
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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