Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED34048.1Conserved hypothetical protein. (294 aa)    
Predicted Functional Partners:
EED34049.1
Conserved hypothetical protein.
       0.707
EED34047.1
3-isopropylmalate dehydratase large subunit 1; [C] COG1049 Aconitase B.
       0.557
EED32900.1
[I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
    
 0.537
EED31664.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
     
 0.510
oadA
Oxaloacetate decarboxylase alpha subunit; [I] COG0511 Biotin carboxyl carrier protein.
    
  0.495
leuD_2
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
       0.467
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
     
  0.435
birA
biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.428
sdhC
[C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
   
    0.417
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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