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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
sucA
[C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
 
 0.989
gltA
[C] COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 0.979
EED32113.1
[C] COG0372 Citrate synthase.
  
 0.978
sdhA
Succinate dehydrogenase, flavoprotein subunit; [O] COG0555 ABC-type sulfate transport system, permease component; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.975
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.969
sdhC
[C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 
 0.966
sdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.
  
 
 0.962
acnB
Aconitate hydratase 2; [G] COG0395 ABC-type sugar transport system, permease component; Belongs to the aconitase/IPM isomerase family.
  
 
 0.948
sdhB
[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.946
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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