| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31684.1 | EED33046.1 | NOR53_3341 | NOR53_1084 | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | 0.585 |
| EED31684.1 | EED33184.1 | NOR53_3341 | NOR53_1287 | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | propionate--CoA ligase (Propionyl-CoA synthetase); [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.419 |
| EED31684.1 | acsA | NOR53_3341 | NOR53_2764 | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.419 |
| EED31684.1 | nadE | NOR53_3341 | NOR53_149 | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.625 |
| EED32423.1 | EED33046.1 | NOR53_2084 | NOR53_1084 | [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | 0.586 |
| EED32423.1 | EED33184.1 | NOR53_2084 | NOR53_1287 | [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | propionate--CoA ligase (Propionyl-CoA synthetase); [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.427 |
| EED32423.1 | acsA | NOR53_2084 | NOR53_2764 | [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.427 |
| EED32423.1 | nadE | NOR53_2084 | NOR53_149 | [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.666 |
| EED33045.1 | EED33046.1 | NOR53_1243 | NOR53_1084 | Conserved hypothetical protein TIGR01777; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases. | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | 0.561 |
| EED33045.1 | EED33047.1 | NOR53_1243 | NOR53_1598 | Conserved hypothetical protein TIGR01777; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases. | DNA photolyase; [L] COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. | 0.566 |
| EED33046.1 | EED31684.1 | NOR53_1084 | NOR53_3341 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase. | 0.585 |
| EED33046.1 | EED32423.1 | NOR53_1084 | NOR53_2084 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.586 |
| EED33046.1 | EED33045.1 | NOR53_1084 | NOR53_1243 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | Conserved hypothetical protein TIGR01777; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases. | 0.561 |
| EED33046.1 | EED33047.1 | NOR53_1084 | NOR53_1598 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | DNA photolyase; [L] COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family. | 0.779 |
| EED33046.1 | EED33184.1 | NOR53_1084 | NOR53_1287 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | propionate--CoA ligase (Propionyl-CoA synthetase); [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.573 |
| EED33046.1 | acsA | NOR53_1084 | NOR53_2764 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.573 |
| EED33046.1 | cinA | NOR53_1084 | NOR53_194 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | Competence/damage-inducible protein CinA; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.629 |
| EED33046.1 | gdhA | NOR53_1084 | NOR53_3097 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.586 |
| EED33046.1 | nadD | NOR53_1084 | NOR53_2825 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.560 |
| EED33046.1 | nadE | NOR53_1084 | NOR53_149 | [K] COG0846 NAD-dependent protein deacetylases, SIR2 family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.827 |