Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED33707.1RNA-metabolising metallo-beta-lactamase; [J] COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing. (469 aa)    
Predicted Functional Partners:
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.949
NOR53_668
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
   
  0.942
pacL
Cation-transporting ATPase, E1-E2 family; [P] COG2217 Cation transport ATPase.
 
 0.786
lepB
[U] COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
   
 
  0.749
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
     
  0.738
NOR53_352
Conserved hypothetical protein TIGR00730; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.
  
    0.738
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
 0.667
EED31275.1
Putative helicase; [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family.
    
 0.667
EED32250.1
Type III restriction enzyme, res subunit family; [LKJ] COG0513 Superfamily II DNA and RNA helicases.
    
 0.667
polA
DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.662
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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