Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
chlDProtoporphyrin IX Magnesium chelatase subunit ChlD; [H] COG1239 Mg-chelatase subunit ChlI. (612 aa)    
Predicted Functional Partners:
bchI
Magnesium chelatase ATPase subunit I; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
 
0.998
bchH
Magnesium chelatase, H subunit; [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.
 
 0.988
bchM
Magnesium protoporphyrin O-methyltransferase; [QR] COG0500 SAM-dependent methyltransferases.
 
 0.965
EED32366.1
Putative magnesium chelatase accessory protein; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
    0.916
EED32395.1
Chlorophyll synthase, (Polyprenyltransferase); [O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor).
 
  
 0.897
bchL
Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
 
  
 0.870
EED32397.1
Geranylgeranyl reductase; [C] COG0644 Dehydrogenases (flavoproteins).
 
  
 0.866
bchF
2-vinyl bacteriochlorophyllide hydratase.
 
  
 0.851
bchJ
Bacteriochlorophyll 4-vinyl reductase.
 
 
 
 0.832
bchC
Chlorophyll synthesis pathway, bchC; [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.
  
 
 0.830
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.