Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
prpRPropionate catabolism operon regulatory protein PrpR; [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains. (512 aa)    
Predicted Functional Partners:
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.906
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
    
 0.899
EED34033.1
CheB methylesterase/CheR methyltransferase; [NT] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.
  
 
 0.892
NOR53_215
[T] COG0642 Signal transduction histidine kinase.
    
 0.811
EED33682.1
[T] COG0642 Signal transduction histidine kinase.
    
 0.811
EED31395.1
Sensor histidine kinase/response regulator; [T] COG0642 Signal transduction histidine kinase.
  
  
 0.787
NOR53_760
[P] COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid.
       0.757
ribB
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.739
NOR53_60
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
     
  0.739
NOR53_690
Hypothetical protein.
     
 0.688
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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