Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED33666.1Diguanylate cyclaSe/phosphodiesterase with PAS/PAC and GAF sensor(s); [T] COG4943 Predicted signal transduction protein containing sensor and EAL domains. (815 aa)    
Predicted Functional Partners:
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
 
 0.988
NOR53_215
[T] COG0642 Signal transduction histidine kinase.
  
 0.980
NOR53_802
Ggdef:eal:histidine kinase, hamp region; [T] COG2200 FOG: EAL domain.
 
 0.973
EED33682.1
[T] COG0642 Signal transduction histidine kinase.
 
 0.972
EED32708.1
PAS sensor diguanylate cyclase and phophodiesterase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
0.927
NOR53_690
Hypothetical protein.
  
 0.921
NOR53_559
Diguanylate cyclaSe/phosphodiesterase with PAS/PAC sensor(s); [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins.
 
0.895
EED31769.1
Ggdef family protein; [T] COG2199 FOG: GGDEF domain.
 
 
0.863
EED32335.1
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
 
 
0.855
EED32126.1
Hamp domain protein; [NT] COG0840 Methyl-accepting chemotaxis protein.
  
 
 0.853
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (12%) [HD]