Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EED33436.1Fumarylacetoacetate hydrolase; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (322 aa)    
Predicted Functional Partners:
EED33435.1
[HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
  
  
 0.807
EED33437.1
Putative metapyrocatechase 2; [E] COG0346 Lactoylglutathione lyase and related lyases.
 
     0.725
EED31826.1
Glyoxylate reductase; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
  0.716
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.664
EED33502.1
Cysteine-rich domain protein; [C] COG0247 Fe-S oxidoreductase.
    
  0.664
allC
[F] COG4266 Allantoicase; Belongs to the allantoicase family.
     
  0.647
ureB
Urease, beta subunit; [E] COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.
     
  0.647
EED32618.1
[C] COG2224 Isocitrate lyase.
     
  0.647
ureC
Urease, alpha subunit; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.
     
  0.647
EED33441.1
Khg/kdpg aldolase; [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.
     
  0.647
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (26%) [HD]