Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED33480.1Glutamate-cysteine ligase, family 2; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (492 aa)    
Predicted Functional Partners:
NOR53_842
Conserved hypothetical protein.
 
     0.925
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
     
  0.739
putA_1
Bifunctional PutA protein; [C] COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase.
     
  0.739
gshB
Glutathione synthase; [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the prokaryotic GSH synthase family.
    
 0.644
EED33192.1
Bacterial NAD-glutamate dehydrogenase superfamily protein; [E] COG2902 NAD-specific glutamate dehydrogenase.
  
  
  0.623
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
  0.569
NOR53_317
Hypothetical protein; [S] COG2308 Uncharacterized conserved protein.
    
  0.561
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
  0.512
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.512
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.511
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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