Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED34020.1Short-chain dehydrogenase/reductase SDR; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (229 aa)    
Predicted Functional Partners:
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
    
  0.740
EED34021.1
[S] COG3686 Predicted membrane protein.
       0.592
NOR53_757
Auxin Efflux Carrier; [R] COG0679 Predicted permeases.
       0.565
NOR53_884
TM2 domain family protein; [S] COG2314 Predicted membrane protein.
       0.559
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.550
EED34051.1
Short-chain dehydrogenase/reductase SDR; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
  0.537
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.537
fabG
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
  0.530
EED31185.1
Oxidoreductase, short chain dehydrogenase/reductase family; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
  0.528
EED33513.1
Oxidoreductase, short chain dehydrogenase/reductase family; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 
 
0.519
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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