Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EED32650.1Peptidase, M13 (neprilysin) family; [O] COG3590 Predicted metalloendopeptidase. (639 aa)    
Predicted Functional Partners:
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
    0.608
polA
DNA polymerase I superfamily protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.602
EED32651.1
Hypothetical protein.
       0.564
EED33499.1
Proton/peptide symporter family protein; [E] COG3104 Dipeptide/tripeptide permease.
  
  
 0.447
EED32415.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
    0.416
NOR53_14
Carbohydrate binding family 6; [R] COG3291 FOG: PKD repeat.
  
    0.416
EED32401.1
Ig family protein; [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain.
  
    0.416
EED33924.1
VCBS protein; [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain.
  
    0.416
EED31316.1
VCBS protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit; overlaps another CDS with the same product name.
  
    0.416
EED31197.1
Conserved repeat domain protein; [UW] COG5295 Autotransporter adhesin.
  
    0.416
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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