Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sulP[R] COG2252 Permeases. (575 aa)    
Predicted Functional Partners:
EED32968.1
Beta-lactamase domain protein; [R] COG0491 Zn-dependent hydrolases, including glyoxylases.
 
     0.898
EED32969.1
Sulfide:quinone oxidoreductase; [C] COG1252 NADH dehydrogenase, FAD-containing subunit.
 
    0.887
putA_1
Bifunctional PutA protein; [C] COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase.
   
 
  0.743
EED32971.1
Hypothetical protein.
       0.740
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.739
EED32226.1
[E] COG0070 Glutamate synthase domain 3.
     
  0.739
NOR53_18
Hypothetical protein; [R] COG1073 Hydrolases of the alpha/beta superfamily.
   
   0.692
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.667
EED32537.1
[C] COG2863 Cytochrome c553.
    
   0.666
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
  0.663
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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