STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EED33109.1tRNA--hydroxylase; [FJ] COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA. (206 aa)    
Predicted Functional Partners:
EED33110.1
Conserved hypothetical protein; [R] COG3313 Predicted Fe-S protein.
 
     0.873
NOR53_771
[S] COG3139 Uncharacterized protein conserved in bacteria.
  
     0.705
NOR53_774
Anti-sigma-factor antagonist; [T] COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).
  
     0.608
sdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.
  
     0.597
yhgI
IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.558
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
     0.540
EED32460.1
Outer membrane protein; [S] COG2135 Uncharacterized conserved protein.
  
     0.516
EED32059.1
Putative conserved hypothetical protein; [R] COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain.
  
     0.509
acnB
Aconitate hydratase 2; [G] COG0395 ABC-type sugar transport system, permease component; Belongs to the aconitase/IPM isomerase family.
       0.491
NOR53_847
Diaminobutyrate-2-oxoglutarate transaminase; [S] COG3101 Uncharacterized protein conserved in bacteria.
  
     0.448
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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