| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EED31538.1 | NOR53_134 | NOR53_2638 | NOR53_134 | Cyclase family protein; [R] COG1878 Predicted metal-dependent hydrolase. | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | 0.454 |
| EED31873.1 | NOR53_134 | NOR53_3563 | NOR53_134 | Protein VisC; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | 0.455 |
| EED31873.1 | ubiA | NOR53_3563 | NOR53_2911 | Protein VisC; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.720 |
| EED31873.1 | ubiB | NOR53_3563 | NOR53_3309 | Protein VisC; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.533 |
| EED31873.1 | ubiG | NOR53_3563 | NOR53_1571 | Protein VisC; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.880 |
| EED33377.1 | NOR53_134 | NOR53_1929 | NOR53_134 | Cyclase family protein; [R] COG1878 Predicted metal-dependent hydrolase. | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | 0.454 |
| NOR53_134 | EED31538.1 | NOR53_134 | NOR53_2638 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | Cyclase family protein; [R] COG1878 Predicted metal-dependent hydrolase. | 0.454 |
| NOR53_134 | EED31873.1 | NOR53_134 | NOR53_3563 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | Protein VisC; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.455 |
| NOR53_134 | EED33377.1 | NOR53_134 | NOR53_1929 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | Cyclase family protein; [R] COG1878 Predicted metal-dependent hydrolase. | 0.454 |
| NOR53_134 | NOR53_183 | NOR53_134 | NOR53_183 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | [R] COG0733 Na+-dependent transporters of the SNF family. | 0.730 |
| NOR53_134 | NOR53_49 | NOR53_134 | NOR53_49 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | [S] COG2914 Uncharacterized protein conserved in bacteria; Belongs to the UPF0125 (RnfH) family. | 0.904 |
| NOR53_134 | acpP | NOR53_134 | NOR53_2257 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.545 |
| NOR53_134 | smpB | NOR53_134 | NOR53_30 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.568 |
| NOR53_134 | ubiA | NOR53_134 | NOR53_2911 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.449 |
| NOR53_134 | ubiB | NOR53_134 | NOR53_3309 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.440 |
| NOR53_134 | ubiG | NOR53_134 | NOR53_1571 | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.514 |
| NOR53_183 | NOR53_134 | NOR53_183 | NOR53_134 | [R] COG0733 Na+-dependent transporters of the SNF family. | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | 0.730 |
| NOR53_183 | NOR53_49 | NOR53_183 | NOR53_49 | [R] COG0733 Na+-dependent transporters of the SNF family. | [S] COG2914 Uncharacterized protein conserved in bacteria; Belongs to the UPF0125 (RnfH) family. | 0.686 |
| NOR53_183 | smpB | NOR53_183 | NOR53_30 | [R] COG0733 Na+-dependent transporters of the SNF family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.563 |
| NOR53_49 | NOR53_134 | NOR53_49 | NOR53_134 | [S] COG2914 Uncharacterized protein conserved in bacteria; Belongs to the UPF0125 (RnfH) family. | Polyketide cyclase/dehydrase family protein; [I] COG2867 Oligoketide cyclase/lipid transport protein. | 0.904 |