Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lys1_1Saccharopine dehydrogenase; [S] COG3268 Uncharacterized conserved protein. (409 aa)    
Predicted Functional Partners:
EED33499.1
Proton/peptide symporter family protein; [E] COG3104 Dipeptide/tripeptide permease.
       0.740
EED33501.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
       0.678
dusC
tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.
       0.661
EED31382.1
Monooxygenase, flavin-binding family; [P] COG2072 Predicted flavoprotein involved in K+ transport.
  
     0.648
EED31665.1
Acyltransferase, ws/dgat/mgat subfamily protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.637
NOR53_545
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.623
atfA
Acyltransferase; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
     0.585
NOR53_136
Molydopterin dinucleotide-binding region; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
     0.565
EED32031.1
Alpha/beta hydrolase fold-3 domain protein; [P] COG2072 Predicted flavoprotein involved in K+ transport.
  
     0.530
EED33920.1
Pgap1 family protein; [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.
  
     0.472
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (12%) [HD]