Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fghAS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (281 aa)    
Predicted Functional Partners:
EED32508.1
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
EED31826.1
Glyoxylate reductase; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.696
EED34056.1
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; [R] COG0388 Predicted amidohydrolase.
   
 
  0.649
EED32507.1
ATP-dependent rna helicase, dead box family; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
       0.583
EED31145.1
Short-chain dehydrogenase EphD; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.567
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.553
EED32254.1
Conserved hypothetical protein.
  
 
  0.551
tesA
acyl-CoA thioesterase I; [E] COG2755 Lysophospholipase L1 and related esterases.
     
 0.544
EED31367.1
Lipase family protein; [I] COG3675 Predicted lipase.
     
 0.538
EED31475.1
Formamidase; [C] COG2421 Predicted acetamidase/formamidase.
     
  0.531
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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