Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
NOR53_138Diguanylate cyclase; [T] COG2199 FOG: GGDEF domain. (456 aa)    
Predicted Functional Partners:
EED31191.1
[T] COG2200 FOG: EAL domain.
 
 
 0.881
EED31684.1
Sensor protein GacS; [T] COG0642 Signal transduction histidine kinase.
 
 0.850
EED33682.1
[T] COG0642 Signal transduction histidine kinase.
 
 0.809
NOR53_215
[T] COG0642 Signal transduction histidine kinase.
  
 0.783
NOR53_559
Diguanylate cyclaSe/phosphodiesterase with PAS/PAC sensor(s); [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins.
 
0.768
EED32335.1
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
 
0.767
NOR53_724
Hypothetical protein; [T] COG2200 FOG: EAL domain; pas:ggdef.
 
0.767
EED32339.1
[T] COG2199 FOG: GGDEF domain.
  
     0.759
NOR53_802
Ggdef:eal:histidine kinase, hamp region; [T] COG2200 FOG: EAL domain.
  
 
 0.745
EED33816.1
Putative diguanylate cyclase (ggdef domain); [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
  
     0.740
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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