STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureCUrease, alpha subunit; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold. (565 aa)    
Predicted Functional Partners:
ureB
Urease, beta subunit; [E] COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.
 0.999
ureA
Urease, gamma subunit; [E] COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.
 0.999
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.996
ureE
Dual specificity protein phosphatase; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.994
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.987
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.943
allC
[F] COG4266 Allantoicase; Belongs to the allantoicase family.
    
  0.754
uraD
OHCU decarboxylase; [S] COG3195 Uncharacterized protein conserved in bacteria.
    
  0.748
allA
[F] COG3194 Ureidoglycolate hydrolase.
    
  0.739
EED32663.1
Conserved hypothetical protein TIGR00370; [E] COG2049 Allophanate hydrolase subunit 1.
     
 0.609
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.