Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EED32546.1Sigma-70, region 4 type 2; [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)    
Predicted Functional Partners:
EED32715.1
Anti-sigma factor MucA; [T] COG3073 Negative regulator of sigma E activity.
  
 0.929
EED32545.1
Conserved hypothetical protein; [K] COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor).
  
 
 0.929
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.880
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.877
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.863
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.839
EED32716.1
Putative negative regulator for alginate biosynthesis; [T] COG3026 Negative regulator of sigma E activity.
 
 0.696
NOR53_158
Flagellar biosynthesis sigma factor FliA; [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Belongs to the sigma-70 factor family.
  
  
 0.667
EED32547.1
Peptidase S8 and S53, subtilisin, kexin, sedolisin; [O] COG1404 Subtilisin-like serine proteases.
 
    0.650
EED33311.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
    0.645
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
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