Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpoE[K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (210 aa)    
Predicted Functional Partners:
EED32715.1
Anti-sigma factor MucA; [T] COG3073 Negative regulator of sigma E activity.
  
 0.971
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.917
EED32716.1
Putative negative regulator for alginate biosynthesis; [T] COG3026 Negative regulator of sigma E activity.
 
 0.912
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.901
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.895
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.884
EED32545.1
Conserved hypothetical protein; [K] COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor).
  
 
 0.734
NOR53_158
Flagellar biosynthesis sigma factor FliA; [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Belongs to the sigma-70 factor family.
  
  
 0.698
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
  
 
 0.695
EED32184.1
[T] COG3806 Anti-sigma factor.
  
 
 0.668
Your Current Organism:
gamma proteobacterium NOR53
NCBI taxonomy Id: 566466
Other names: g. proteobacterium NOR5-3, gamma proteobacterium NOR5-3
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.